Open trials, data resources and primary literature for H3 K27M altered diffuse midline glioma, kept in one place.
Where DMG tissue, molecular data and reference material actually live. Access terms differ: some are open, some controlled, and some require a project application.
Everything indexed on PubMed in the last weeks matching diffuse midline glioma, diffuse intrinsic pontine glioma or H3K27M, newest first, added automatically each day. This is a raw feed: case reports and reviews sit beside primary research, and nothing here has been filtered for quality.
Where DMG specific research money comes from, and the Canadian brain tumour funders that also support this work. Deadlines move each year, so check each call directly.
Interventional studies open or opening to accrual that list diffuse midline glioma or diffuse intrinsic pontine glioma among their conditions. Each row links to its ClinicalTrials.gov record, which is the authoritative source for eligibility and sites.
| Study | Phase | Approach | Sponsor | Status | Record |
|---|---|---|---|---|---|
| Loading the trial table. | |||||
The full, live list is at ClinicalTrials.gov, which held 51 interventional DMG or DIPG studies recruiting or about to recruit when this page was last reviewed.
Work that has not been through a journal yet, and the places where people write about the field between papers. Preprints are not peer reviewed; read them as claims rather than conclusions.
A working bibliography of 53 papers, each verified against its PubMed record. Grouped by what the paper is for rather than by date.
Compiled by Arun Kumaran Anguraj Vadivel, Molecular Medicine, The Hospital for Sick Children, Toronto. Open trials and newly published papers refresh automatically each day from ClinicalTrials.gov and PubMed; the curated sections are reviewed by hand. It is a research reference, not medical advice, and treatment decisions belong with a patient's own care team.
This is a personal research reference maintained alongside work on DMG proteomics and functional omics at SickKids. It is not affiliated with any consortium, registry or sponsor, and inclusion here is not an endorsement of a trial or a product. Trial status changes constantly, so treat the ClinicalTrials.gov record as current and this table as a snapshot.
Corrections, additions and links worth including are welcome: arun.angurajvadivel@sickkids.ca